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© 2010 The Shi Laboratory

pre-mRNA splicing
 

The structure of the intact spliceosome from S. pombe at 3.6 angstrom provides insights into the molecular mechanism of pre-mRNA splicing.
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Intramembrane
Proteolysis

The structure of the four-component membrane complex γ-Secretase.
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Apoptosis
 

The structure of the mammalian Apaf-1 apoptosome.
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